Ozone therapy is a natural, science-based treatment that uses medical-grade ozone (O₃)—a molecule made up of three oxygen atoms—to support and stimulate the body’s innate healing processes. When used therapeutically in a controlled medical setting, ozone can provide powerful benefits for individuals facing chronic illness, fatigue, inflammation, infections, and immune dysfunction.

Unlike the ozone found in environmental pollution, medical ozone is created using pure oxygen and is administered in precise concentrations by trained professionals like Dr. Linette Williamson. It’s one of the most effective non-pharmaceutical tools available in integrative medicine today.

How Ozone Therapy Works

When ozone is introduced into the body—whether through blood infusion, joint injections, or insufflation—it triggers a cascade of positive biological responses:

Enhances oxygen metabolism
Ozone therapy improves the body’s ability to use oxygen more efficiently at the cellular level. This boosts mitochondrial function (your body’s energy factories), which is especially beneficial for those with fatigue, brain fog, and poor circulation.
Promotes natural detoxification
Ozone stimulates liver enzymes and antioxidant defenses like glutathione, helping the body neutralize toxins, clear inflammation, and reduce oxidative stress—a major contributor to chronic disease.
Modulates and strengthens the immune system
Whether your immune system is underactive (e.g., chronic infections, long COVID) or overactive (e.g., autoimmune diseases), ozone therapy helps rebalance immune function, making it smarter—not just stronger.

These properties make ozone therapy an excellent option for a wide range of conditions, especially those that haven’t responded to conventional treatments alone.

Conditions Treated with Ozone Therapy

Chronic Fatigue, Brain Fog, and Fibromyalgia

If you’re feeling constantly drained, mentally foggy, or achy for no clear reason, ozone therapy may help. By improving mitochondrial function (your body’s energy production system) and reducing systemic inflammation, ozone therapy supports sustainable energy, mental clarity, and reduced muscle pain—especially for fibromyalgia sufferers.

Autoimmune Conditions

(Lupus, Rheumatoid Arthritis, Hashimoto’s)

Ozone therapy helps calm an overactive immune system while also reducing oxidative stress—a key driver of autoimmune flare-ups. Dr. Linette has used ozone therapy as part of a broader treatment plan to help patients with autoimmune disease feel more stable, less inflamed, and more in control of their health.

Chronic Infections: Lyme, Epstein-Barr, Mold Illness

These complex infections can linger for months or years, often resisting conventional antibiotics or antivirals. Ozone therapy enhances the immune response and creates an environment that’s hostile to bacteria, viruses, and fungi—making it a powerful ally in the fight against chronic Lyme, reactivated Epstein-Barr, and biotoxin illness from mold exposure.

Long COVID Symptoms

Post-COVID symptoms like fatigue, brain fog, chest tightness, and poor circulation are often the result of lingering inflammation and immune dysregulation. Ozone therapy has shown promising results for long COVID patients by rebalancing the immune system, reducing viral load, and restoring cellular oxygenation.

Joint Pain and Degenerative Conditions

(Arthritis, Back Pain, Joint Degeneration)

Whether from aging, injury, or chronic wear and tear, joint pain can severely impact daily life. Through Prolozone therapy, Dr. Linette injects a combination of medical ozone and healing nutrients directly into painful joints and tissues, promoting regeneration, pain relief, and improved mobility—without surgery.

Cardiovascular and Circulatory Issues

Ozone therapy helps improve blood flow, oxygen delivery, and vascular flexibility, which can support patients dealing with high blood pressure, poor circulation, or recovery from cardiovascular stress. It also helps prevent oxidative damage, a major factor in heart and arterial disease.

Immune System Dysfunction

Frequent illness? Never fully recovering? Feeling like your immune system is either “asleep” or attacking your own tissues? Ozone therapy acts as a natural immune modulator, helping restore healthy immune function—neither overreactive nor underactive.

Toxin Overload, Gut Dysfunction, and Chronic Inflammation

Environmental toxins, a leaky gut, or an overwhelmed liver can contribute to a wide range of symptoms, from headaches and bloating to skin issues and brain fog. Ozone therapy enhances detox pathways and supports gut healing, making it a valuable part of any functional medicine detox program.

Ozone Therapy Methods Offered at Dr. Linette’s Clinic

EBOO Therapy (Extracorporeal Blood Oxygenation and Ozonation)

EBOO is considered the most advanced form of systemic ozone therapy available today, and Dr. Linette is one of the few providers in Southern California offering it.

How it Works:

During EBOO therapy, a small amount of your blood is gently drawn and passed through a specialized medical device where it is filtered, ozonated, and enriched with oxygen. The blood is then safely returned to your body in real-time through a second IV line.

Benefits of EBOO:

Deep detoxification at the cellular level
Powerful immune system reset
Enhanced oxygen delivery and circulation
Reduction of chronic inflammation and infections

EBOO is ideal for patients with autoimmune conditions, long COVID, mold illness, chronic fatigue, and those seeking a full-body healing experience.

IV Ozone Therapy (Major Autohemotherapy)

Also known as MAH, this classic and widely used form of ozone therapy delivers benefits across the entire body.

How it Works:

A small amount of your blood is drawn, mixed with medical-grade ozone, and then infused back into your bloodstream through an IV. It’s a quick, safe, and effective treatment that many patients find energizing and restorative.

Benefits of IV Ozone:

Boosts immune function and resilience
Improves cellular energy (ATP) production
Aids in recovery from chronic infections or inflammation
Helps manage fatigue, brain fog, and mood imbalances

This therapy is commonly used for chronic viral infections, autoimmune flares, and general wellness support.

Prolozone Therapy (for Pain & Joint Health)

Prolozone therapy is a non-surgical, regenerative treatment that combines ozone gas with healing nutrients like vitamins, minerals, and homeopathic solutions. It is injected directly into joints, ligaments, or soft tissues to support tissue repair and pain relief.

Effective For:

Arthritis (knees, hips, shoulders)
Degenerative disc disease or back pain
Sports injuries or overuse conditions
Post-surgical healing and inflammation

By increasing oxygenation and stimulating collagen repair, Prolozone offers a powerful alternative to corticosteroid injections or invasive orthopedic procedures.

Ozone Insufflation (Rectal & Vaginal)

(Gentle Internal Therapy for Detox and Immune Health)

Ozone insufflation is a safe, needle-free method that introduces low-pressure ozone gas into the body via the rectum or vaginal canal. It allows ozone to be absorbed through mucosal tissue, reaching systemic circulation and affecting the gut, liver, lymph, and reproductive organs.

Used For:

Digestive issues (e.g., IBS, leaky gut, candida)
Liver detoxification and gut microbiome support
Pelvic inflammation or recurrent infections
Systemic immune boosting

This gentle therapy is especially popular for those who prefer non-invasive, non-IV options to receive the benefits of ozone.

Topical Ozone & Ozone Bagging

(Targeted Skin & Tissue Healing)

For patients with external wounds, infections, or inflammatory skin issues, topical ozone therapy and ozone bagging provide an effective way to promote healing and fight infection—without antibiotics or harsh chemicals.

Conditions Treated:

Slow-healing wounds and post-surgical incisions
Fungal infections or athlete’s foot
Skin conditions like eczema, psoriasis, or dermatitis
Diabetic ulcers or circulation-related skin issues

With ozone bagging, a limb or area of the body is enclosed in a special bag that is gently filled with ozone gas, allowing the skin to absorb ozone deeply and safely.

Reclaim Your Energy, Immunity & Vitality—Naturally

Are you tired of living with fatigue, chronic pain, brain fog, or unexplained inflammation? Have conventional treatments failed to give you long-term relief? Ozone therapy could be the breakthrough you’ve been searching for.

At her integrative clinic just outside Escondido, Dr. Linette Williamson offers safe, science-backed ozone therapies tailored to your body’s specific needs. Whether you're managing a complex chronic condition or looking to detox and revitalize your system, Dr. Linette’s approach treats the root—not just the symptoms.

With over 30 years of clinical experience, including 15 years in emergency medicine and 15+ in integrative and functional medicine, Dr. Linette combines advanced diagnostics, cutting-edge treatments like EBOO and Prolozone, and a deeply compassionate, personalized care philosophy.