What is EBOO and How Does It Work?
EBOO stands for Extracorporeal Blood Oxygenation and Ozonation—an advanced form of ozone therapy that goes far beyond conventional methods. The process involves removing a portion of a patient's blood, infusing it with a precise mixture of oxygen and ozone, filtering it through a medical-grade dialysis-like system, and returning it to the body. This is all done using a closed-loop, sterile circuit that ensures both safety and efficacy.
The goal of EBOO is to detoxify the blood, oxygenate tissues, and modulate the immune system, making it a promising therapy for individuals experiencing chronic autoimmune flare-ups.
How Is EBOO Different from Other Ozone Therapies?
While ozone therapy itself isn’t new, EBOO represents the most advanced and comprehensive version of this approach available today. Here’s how it compares:
- MAH (Major Autohemotherapy): Involves withdrawing a small amount of blood, mixing it with ozone, and re-infusing it. Useful, but limited in volume and detox capacity.
- 10-Pass Ozone Therapy: A step up in intensity, involving ten passes of blood ozonation, but still lacks filtration and continuous circulation.
- EBOO: Continuous circulation and filtration of up to 2.5 liters of blood in a single session. It is the only method that simultaneously oxygenates, ozonates, and purifies the blood in real-time—offering a deeper and more dynamic therapeutic impact.
What Makes EBOO Unique in Integrative Care?
Deeper Detoxification
EBOO clears the bloodstream of metabolic waste, heavy metals, and microbial toxins—offering a level of purification not possible with other ozone therapies.
Enhanced Immune Regulation
Rather than suppressing immune activity, EBOO balances immune response, reducing hyperinflammation without compromising immune defense.
Superior Circulation and Oxygen Delivery
Oxygen is life—and with EBOO, your blood is supercharged with it. This improves mitochondrial function, supports tissue repair, and enhances overall vitality.
Biofilm and Pathogen Clearance
Pathogens often hide in biofilms, which conventional medicine struggles to penetrate. EBOO breaks down these barriers, allowing the body to more effectively eliminate hidden infections.
Understanding Autoimmune Flare-Ups
An autoimmune flare-up occurs when the body’s immune system—mistakenly attacking its own tissues—suddenly becomes more aggressive or reactive, intensifying symptoms and often disrupting daily life. These episodes can come on suddenly or gradually and may last days, weeks, or even months depending on the individual and underlying condition.
Flare-ups are characteristic of chronic autoimmune diseases such as lupus, rheumatoid arthritis, Hashimoto’s thyroiditis, psoriasis, and multiple sclerosis—all of which can ebb and flow in intensity.
Common Symptoms of Flare-Ups
During a flare, patients often experience a worsening of baseline symptoms or the emergence of new ones. Common complaints include:
- Persistent fatigue that doesn’t improve with rest
- Inflammation and swelling in joints or tissues
- Joint pain and stiffness, often symmetrical in nature
- Brain fog, memory lapses, and difficulty concentrating
- Digestive issues, such as bloating, IBS, or nausea
- Skin rashes, flare-related fevers, or flulike symptoms
What Triggers Autoimmune Flare-Ups?
Understanding what causes these flares is critical for both prevention and treatment. While triggers can vary widely from person to person, common culprits include:
- Chronic stress – Psychological stress is known to alter immune function and hormone balance
- Environmental toxins – Exposure to mold, heavy metals, pesticides, or household chemicals can provoke an immune response
- Gut dysbiosis – Imbalances in gut bacteria or intestinal permeability (leaky gut) may ignite immune overactivity
- Viral reactivations – Latent viruses like Epstein-Barr or herpes family viruses can silently provoke flares when reactivated
EBOO’s Immune-Modulating Benefits
How EBOO Affects the Immune System
Balancing Pro- and Anti-Inflammatory Cytokines
Autoimmune flare-ups are often driven by an overproduction of pro-inflammatory cytokines, which create a cascade of pain, fatigue, and tissue damage. EBOO has been shown to downregulate these inflammatory messengers while promoting the production of anti-inflammatory cytokines. This recalibration helps the immune system regain its natural rhythm without the blunt force of immunosuppressants.
Removing Inflammatory Byproducts and Immune Complexes
As EBOO continuously filters and ozonates the blood, it removes oxidized debris, immune complexes, and metabolic waste that can fuel chronic inflammation. This purification process lightens the immune system’s load and helps restore clarity and function to the body’s regulatory networks.
Research Highlights Supporting Ozone Therapy
NIH-Backed Studies
Multiple studies supported by the National Institutes of Health (NIH) and other medical institutions have examined the effects of ozone therapy on the immune system. Research shows that medical ozone can stimulate antioxidant defenses, improve oxygen utilization, and regulate immune activity in autoimmune and infectious diseases.
Clinical Outcomes in Autoimmune Disorders
Clinical observations of EBOO in patients with conditions like lupus, rheumatoid arthritis (RA), and multiple sclerosis (MS) have shown improvements in symptom frequency, severity, and duration. Patients often report fewer flare-ups, reduced medication dependency, and an overall improvement in vitality and function.
Patient-Reported Benefits of EBOO for Autoimmunity
The benefits of EBOO go beyond lab values—they’re reflected in real-life results. At Dr. Linette Williamson’s practice, patients dealing with chronic autoimmunity consistently report:
- Fewer and less intense flare-ups
Many patients notice a dramatic reduction in inflammation, joint pain, and fatigue after just a few sessions. - Improved energy, mood, and cognitive clarity
By enhancing oxygen delivery and reducing systemic inflammation, EBOO helps restore natural energy levels and mental focus—two areas commonly diminished during autoimmune flares. - Minimal side effects compared to conventional treatments
Unlike pharmaceuticals that often come with long lists of risks, EBOO offers a gentle yet powerful therapeutic option with little to no downtime and excellent tolerability.
Questions Patients Should Ask Before Starting EBOO
Safety & Expectations
“Is EBOO safe for my specific autoimmune condition?”
Not all autoimmune conditions present the same way. It’s important to confirm that EBOO is appropriate for your diagnosis, whether it's lupus, rheumatoid arthritis, Hashimoto’s, or another chronic inflammatory disease. Dr. Williamson conducts a thorough evaluation to determine if you’re a good candidate, considering factors like medication use, coexisting conditions, and overall immune function.
“What should I expect during and after the session?”
Understanding the process helps reduce anxiety. EBOO is typically well-tolerated and takes about 60–90 minutes. Most patients experience a sense of clarity and lightness afterward, though mild detox symptoms (like fatigue or achiness) may occur temporarily as the body recalibrates. You’ll be monitored closely before, during, and after your session.
Treatment Plan
“How many sessions are recommended for autoimmune regulation?”
EBOO is most effective when delivered as part of a personalized treatment protocol. While some patients see noticeable results after one session, chronic autoimmune patients typically benefit from a series—often 4 to 10 sessions spaced weekly or biweekly. Dr. Williamson customizes each plan based on your health history, labs, and symptom response.
“Is EBOO a standalone treatment or part of a larger plan?”
At this practice, EBOO is rarely used in isolation. It is integrated into a whole-body healing plan that may include hormonal balancing, targeted nutritional support, advanced light therapies (like TheraLumen and HemaLumen), and lifestyle coaching to optimize outcomes.
Integration with Other Therapies
“Can EBOO be combined with my current medications?”
Yes—and in many cases, patients are able to reduce their reliance on certain medications over time under medical supervision. Dr. Williamson carefully reviews your prescriptions to ensure compatibility and safety, adjusting the plan as needed to avoid interactions or overstimulation.
“What other holistic therapies do you recommend with EBOO?”
For autoimmune patients, EBOO pairs beautifully with therapies like gut restoration protocols, detoxification support, bioidentical hormone balancing, and hyperbaric oxygen therapy. Combining modalities amplifies healing and builds long-term resilience.
Provider Credentials
“What experience do you have treating autoimmune patients with EBOO?”
Dr. Linette Williamson brings over 15 years of integrative medicine expertise—combined with ER experience—to her practice. She has treated hundreds of patients with complex autoimmune conditions, using EBOO as a cornerstone in her personalized healing protocols.
“Are you using certified equipment (e.g., Hyperbaric Ozone Barrier systems)?”
Yes. Only certified Hyperbaric Ozone Barrier systems are used in the clinic to ensure the highest standard of sterility, safety, and efficacy. These systems are designed specifically for advanced ozone therapy, with precise ozone concentrations, medical-grade filters, and closed-loop circulation to prevent contamination.
Your Path to Autoimmune Relief Starts Here
EBOO (Extracorporeal Blood Oxygenation and Ozonation) is more than an emerging therapy—it’s a powerful, science-backed solution for restoring immune balance and addressing the root causes of autoimmune flare-ups. Unlike conventional treatments that suppress symptoms, EBOO works with your body to detoxify, oxygenate, and modulate immune function, making it one of the most promising integrative tools available today.
Whether you're navigating chronic fatigue, joint pain, or unpredictable autoimmune symptoms, EBOO offers a safe and effective path to long-term relief—all within a personalized care plan that supports every layer of your health.
📞 Contact Dr. Linette Williamson Today
- Phone: (760) 875-2627
- Website: www.LinetteWilliamsonMD.com
- Visit Us: 317 North El Camino Real, Suite 107, Encinitas, CA 92024
- Telehealth Available in Florida
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