Ozone therapy is a powerful, science-backed treatment that uses medical-grade ozone (O₃)—a highly energized form of oxygen—to stimulate healing throughout the body. Unlike the environmental ozone associated with pollution, the ozone used in medical therapy is carefully generated in a controlled setting and administered by trained professionals like Dr. Linette Williamson.

At its core, ozone therapy works by enhancing the body's ability to heal itself naturally. When introduced into the body, ozone interacts with blood, tissue, and immune cells in a way that increases oxygen delivery, improves cellular metabolism, and activates the body's antioxidant defenses. This makes it a highly effective therapy for a wide range of chronic and inflammatory conditions.

How Does Ozone Therapy Work?

When introduced intravenously, topically, or via other therapeutic methods, ozone therapy supports the body in several key ways:

Improves oxygen utilization at the cellular level
Ozone enhances mitochondrial function—your cells’ energy centers—helping them produce more ATP (energy), which is essential for healing and regeneration.
Boosts immune system response
It modulates immune function, making it especially helpful for autoimmune conditions and chronic infections like Lyme disease, Epstein-Barr virus, and long COVID.
Reduces systemic inflammation
Ozone has anti-inflammatory effects that help reduce pain, stiffness, and swelling—particularly in conditions like arthritis, fibromyalgia, and chronic fatigue.
Supports detoxification
Ozone therapy helps neutralize toxins, support liver function, and clear oxidative stress, assisting patients who struggle with environmental illness or mold toxicity.
Enhances circulation and oxygen delivery to tissues
Better blood flow means improved healing in hard-to-reach tissues, including joints, nerves, and the brain.

Conditions Treated with Ozone Therapy

Chronic Fatigue & Fibromyalgia

Patients suffering from unrelenting fatigue, muscle pain, and poor recovery often benefit from ozone therapy. By improving mitochondrial function and enhancing oxygen delivery at the cellular level, ozone helps restore energy production, reduce inflammation, and improve overall vitality—naturally and without stimulants.

Autoimmune Diseases (Lupus, Rheumatoid Arthritis, Hashimoto’s)

Ozone therapy helps modulate immune activity, making it highly effective for autoimmune conditions. It calms overactive immune responses while reducing oxidative stress, offering relief from joint pain, inflammation, and fatigue in conditions like rheumatoid arthritis, lupus, and thyroid autoimmunity.

Chronic Infections: Lyme Disease, Epstein-Barr, Mold Illness

Chronic infections often persist due to a weakened or dysregulated immune system. Ozone therapy enhances immune resilience and creates an environment that is inhospitable to viral, bacterial, fungal, and parasitic pathogens. It also helps detoxify mycotoxins for those suffering from mold exposure and biotoxin illness.

Joint and Musculoskeletal Pain

From arthritis and joint degeneration to muscle strains and overuse injuries, ozone can be injected directly into affected tissues (Prolozone Therapy) to stimulate regeneration, reduce inflammation, and relieve pain. Many patients report improved mobility and pain reduction after just a few sessions.

Long COVID Symptoms and Respiratory Conditions

Ozone therapy supports recovery from lingering COVID symptoms including fatigue, brain fog, breathlessness, and inflammation. It can also benefit those with chronic respiratory illnesses like asthma or COPD, by improving oxygenation and reducing airway inflammation.

Cardiovascular Issues and Poor Circulation

Ozone therapy enhances blood flow, reduces clotting risks, and supports the oxygenation of tissues—making it valuable for patients with high blood pressure, poor circulation, and those recovering from cardiovascular stress. It’s also beneficial in improving capillary perfusion in diabetic patients with peripheral vascular issues.

Detoxification and Liver Support

Your liver is your body’s natural detox powerhouse—but in today’s toxic environment, it can become overwhelmed. Ozone supports liver enzyme activity and glutathione production, making it an excellent therapy for patients undergoing detox programs, recovering from toxic exposures, or dealing with sluggish liver function.

Brain Fog and Neurological Inflammation

Ozone’s ability to increase oxygen delivery to the brain makes it especially helpful for cognitive symptoms like brain fog, memory issues, and poor concentration. Patients recovering from neurological Lyme, long COVID, or mold illness often notice clearer thinking and improved mental stamina.

Immune Dysfunction and Recurring Illness

If you're the type of person who "catches everything," your immune system may be operating below optimal function. Ozone therapy strengthens and balances immune responses, helping to prevent frequent infections and reduce the severity and duration of illness.

Ozone Therapy Delivery Methods at Dr. Linette’s Clinic

EBOO (Extracorporeal Blood Oxygenation and Ozonation)

EBOO represents the most sophisticated form of systemic ozone therapy in the world—and Dr. Linette is one of the few providers in the San Diego area offering this cutting-edge treatment.

What is EBOO?

EBOO is a high-tech, full-body detox and immune optimization procedure that goes beyond traditional IV ozone. It involves gently withdrawing your blood, filtering it through a specialized system to remove inflammatory byproducts, then infusing it with medical-grade ozone and oxygen before returning it to your body.

Key Benefits of EBOO:

Deep detoxification at the cellular and circulatory level
Immune system reset for those with autoimmune or chronic infections
Increased energy and mental clarity after just one session
Reduction of viral, fungal, and bacterial load in the bloodstream
Support for neurological and cardiovascular health

Ozone Insufflation (Rectal and Vaginal)

Ozone insufflation is a gentle and highly effective internal ozone therapy that delivers healing directly to the gut, pelvic organs, and immune tissues, where much of the body’s immune and inflammatory activity begins.

Rectal Ozone Insufflation:

This method introduces ozone gas into the lower colon, where it is absorbed through the intestinal lining into the bloodstream, offering benefits similar to IV ozone—without the need for a needle.

It’s especially beneficial for:

Digestive issues (IBS, leaky gut, dysbiosis)
Detoxification and liver support
Systemic inflammation and fatigue
Immune strengthening and chronic infections

Vaginal Ozone Insufflation:

A safe, low-pressure treatment used to support:

Chronic yeast infections and bacterial vaginosis
Pelvic inflammatory conditions
Hormonal balance and detox support

IV Ozone Therapy (MAH – Major Autohemotherapy)

IV ozone therapy is one of the most established forms of systemic ozone treatment. It involves drawing a small amount of your blood, mixing it with medical-grade ozone, and then gently infusing the ozonated blood back into your body via an IV.

This process allows ozone to interact directly with your immune system, red blood cells, and mitochondria—enhancing oxygen delivery and reducing inflammation throughout your body.

Benefits of IV Ozone Therapy:

Boosts energy production and mitochondrial health
Reduces chronic inflammation and oxidative stress
Supports immune modulation in autoimmune or infectious conditions
Aids in recovery from long COVID, chronic fatigue, and Lyme disease

Prolozone Therapy: Joint and Pain Relief

Prolozone therapy is a powerful treatment that combines ozone gas with vitamins, minerals, and anti-inflammatory nutrients, injected directly into painful or damaged joints and tissues.

It’s an ideal option for patients seeking non-surgical relief from chronic pain, and it's commonly used to treat:

Knee, shoulder, and hip pain
Lower back pain and sciatica
Arthritis and joint degeneration
Sports injuries and repetitive strain

Topical Ozone Therapy & Ozone Bagging

For patients dealing with external wounds, infections, or skin conditions, Dr. Linette offers topical ozone treatments and ozone bagging, a localized therapy where a limb or area of the body is enclosed in a special bag filled with ozone gas.

These therapies are especially effective for:

Slow-healing wounds (including diabetic ulcers)
Eczema, psoriasis, and dermatitis
Fungal infections or skin-related inflammation
Post-surgical healing support

Take the Next Step Toward Healing and Whole-Body Wellness

Are you ready to restore your energy, reduce inflammation, and feel like yourself again? Whether you’ve been living with chronic fatigue, autoimmune issues, long COVID symptoms, or persistent joint pain, ozone therapy may be the solution you’ve been searching for.

At her peaceful, state-of-the-art clinic in Encinitas—just a short drive from El Cajon—Dr. Linette Williamson offers a unique blend of science, safety, and holistic healing. With more than 30 years of combined experience in emergency and integrative medicine, she provides one of the most advanced and trusted ozone therapy programs in San Diego County.